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The Discount Reached the Boardroom

Sep 11, 2026

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11 min read

The Discount Reached the Boardroom

The FDA paused Biohaven's pivotal epilepsy enrollment fifteen days after its up to $795M SK deal, an Artisan Partners manager demanded Novartis board changes, Axogen paid $200M for sutureless nerve repair, and the surrogate discount week closed with nothing round tripped.

BioMed Nexus
BioMed Nexus

THE LATEST


Sep 10, 2026

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9 min read

Three Toplines, Zero Numbers

BMS' arlo-cel cleared its pivotal myeloma trial with the data held for a congress, Bayer's Hyrnuo won first line lung cancer approval on a 75% response rate, the FDA's drug and biologics chiefs went permanent, and three private rounds raised $550 million in a day.

Sep 9, 2026

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9 min read

Amgen Paid for Novartis' Miss

Del-desiran failed its Phase 3 with the numbers withheld, Amgen dropped 10.1% on Lp(a) readacross despite an Imdelltra survival win, the FDA approved Etcamah over its advisers' no vote, and Boston Scientific told the SEC its guidance is out of reach.

Sep 8, 2026

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9 min read

The Number Went Down. The Risk Didn't.

Pelacarsen and ziltivekimab failed outcomes tests four days apart, semaglutide moved 40.4% of children out of obesity, and Menarini priced ledger entry #14 at exactly 8.5%. Plus Boston Scientific's recall and recovery, and the week's through line.

TRENDING


The Bispecific That Beat Keytruda

The Bispecific That Beat Keytruda

Ivonescimab cleared the survival bar against pembrolizumab in China and kept the numbers, Ultragenyx's Angelman Phase 3 failed, and GSK paid $110M upfront for a preclinical KRAS conjugate. Plus the week's delivered catalyst tally: 1 of 13.

The Ex Vivo Exit Queue

The Ex Vivo Exit Queue

TScan cut 75% and listed its autoimmune program, Novartis paid up to $3.2B for Alteogen's delivery enzyme, and uniQure filed the first Huntington's gene therapy BLA. Plus the Medicare GLP-1 numbers and Teva's celiac win.

The Day Autoimmune CAR T Hit the Wall

The Day Autoimmune CAR T Hit the Wall

Novartis and BMS paused their autoimmune CAR T programs after patient deaths while Roche paid $75M upfront for Simcere's B cell trispecific. Plus REMODEL's clean liver, the Alumis lupus wipeout, and GSK's mRNA flu Phase 3.

The MFN Deal Came, the Biotechs Didn't

The MFN Deal Came, the Biotechs Didn't

Nine drugmakers joined the White House pricing program and none of them was the midsize biotech the story was about. Plus Lilly's up to $2.875B Merida buy, BioMarin's 20% royalty, and Monday's delivered catalyst tally.

Five Catalysts Delivered, Five Stocks Down

Five Catalysts Delivered, Five Stocks Down

The FDA's queue delivered Mimrylo and Lisraya, Mounjaro got a non inferiority heart label, and ESC repriced numbers the market already had.

Four Dates, Zero Decisions

Four Dates, Zero Decisions

The empty date week ends in a ratio: Boston Scientific's cyberattack, Tezspire's numberless Phase 3 win, and the only actors who beat their clocks.

The FDA Showed Up Early

The FDA Showed Up Early

The first broad RAS drug in pancreatic cancer arrived ahead of schedule. Plus Ziihera's seven month survival gain, Biohaven's $795M exit, and the question we said we would ask.

The $1.5B Deal That Skipped the IPO Window

The $1.5B Deal That Skipped the IPO Window

ARCH and Population Health launch Sentivera around a preclinical Haisco asset. Plus the IPO window nears escape velocity, Foundayo lands in the UK, and the empty date tally holds at zero.

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