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LATEST ISSUES


AI Pivot in Biotech: GRAIL FDA Move + $500M Deal

AI Pivot in Biotech: GRAIL FDA Move + $500M Deal

GRAIL's multi-cancer test PMA filed • Formation's $500M autoimmune buy • RFK Jr. revamps Alzheimer's priorities • Oracle's AI data launch

Capital Reprices the Stack ($257M Bet)

Capital Reprices the Stack ($257M Bet)

Cell therapy manufacturing pivots to scale, Quadruplet myeloma becomes standard, AAV safety pressure rises

The Repricing of Managed Care: UNH -20% on Rate Shock, Intellia Lift

The Repricing of Managed Care: UNH -20% on Rate Shock, Intellia Lift

UnitedHealth crashes on MA rate shock & guidance cut; Intellia clears partial CRISPR hold; Resonetics M&A and Boston Scientific updates inside.

Capital Gets Conditional (UNH Sets the 2026 Baseline)

Capital Gets Conditional (UNH Sets the 2026 Baseline)

Sarepta’s 3-year durability resets gene therapy risk, UnitedHealth earnings frame utilization pressure, FDA tightens MRD expectations.

Monday Brief: Capital Gets Conditional

Monday Brief: Capital Gets Conditional

Why milestone-heavy deals, AI workflows, and payer rules now shape execution risk.

BMS Bets $850M on Janux; Corxel’s Massive Series D

BMS Bets $850M on Janux; Corxel’s Massive Series D

Janux secures $850M BMS deal; Corxel raises $287M for oral obesity; Mendra launches with $82M.