BioMed Nexus Daily Updates

Your essential biotech, medtech, and pharma recap — no noise, just what matters.

🔮 Pre-Market Download

The "Dilution Divergence" & A Prostate Cancer Win: Wednesday’s trading session highlighted a critical shift in institutional sentiment: Biotech financing is back, but the market is discriminating.

  • The Winner: Kodiak Sciences (KOD) upsized its offering to $160M and the stock rallied +11.7%. Investors are hungry for late-stage, high-conviction assets.

  • The Loser: Immunome (IMNM) priced a $400M offering and sold off -15.7%, punishing the "platform premium" in favor of clinical certainty.
    👉 Read more

Meanwhile, Pfizer (PFE) continued its slide (-1.9%) as Wall Street digests the soft 2026 guidance, and the FDA handed out a full approval in prostate cancer to a post-bankruptcy asset.

  • Market Watch: Recursion (RXRX) bounced +11.4% yesterday as AI-bio sentiment stabilized.

  • Macro: The XBI outperformed the S&P 500, suggesting a "Risk On" rotation into Q1 2026.
    👉 Read more

💉 Top Stories

  • Kodiak Sciences (KOD) Defies Gravity: Typically, secondary offerings crush biotech stocks. Yesterday, Kodiak upsized its raise to $160M at $23.00/share, and the stock closed near $27.00. The "oversubscribed" deal for its Phase 3 retina pipeline signals that deep-pocketed funds are deploying cash into late-stage readouts for 2026. 👉 Read more

  • FDA Grants Full Approval to Rubraca: The FDA converted the accelerated approval of Rubraca (rucaparib) to full approval for BRCA-mutated metastatic castration-resistant prostate cancer (mCRPC). Pharmaand GmbH (which acquired the asset from the bankrupt Clovis Oncology) scored the regulatory win based on the TRITON3 trial showing a significant radiographic progression-free survival benefit. 👉 Read more

  • Immunome (IMNM) Punished on Pricing: Despite the positive desmoid tumor data earlier in the week, Immunome shares tanked -15% after pricing a massive $400M offering. The sheer size of the dilution outweighed the clinical win, a reminder that "valuation discipline" has returned.

  • Capricor (CAPR) Webinar Reaction: Following its 1:00 PM ET webinar on the Phase 3 HOPE-3 data, Capricor saw elevated volume. Management reinforced the "disease modifying" potential of deramiocel in Duchenne Muscular Dystrophy, aiming to file a BLA promptly. The stock remains a battleground over the commercial ramp speed. 👉 Read more

🔬 Clinical Pulse

  • Nektar (NKTR) Stays Weak: Down another -7.6% yesterday. The market is rejecting the "post-hoc" success narrative for its alopecia drug. Without a clean primary endpoint hit, the path to a partner is murky. 👉 Read more

  • Recursion (RXRX) Rebounds: After a "Sell the News" reaction earlier in the week, RXRX buyers stepped in at the $3.80 level, driving a +11% bounce. Volatility will remain high as the AI-drug discovery thesis faces scrutiny. 👉 Read more

📊 Market Snapshot (Wednesday Close)

Ticker

Close

Change

Note

KOD

$26.97

+11.8%

Upsized offering digested aggressively.

RXRX

$4.68

+11.4%

Technical bounce off support.

PFE

$25.04

-1.9%

New lows on "Guidance Reset".

IMNM

$19.78

-15.8%

Dilution hangover from $400M raise.

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